July 31, 2012 — Allopurinol hypersensitivity syndrome (AHS), a rare but potentially fatal adverse reaction in patients beginning allopurinol therapy for gout, might be largely avoided by keying the ...

Please provide your email address to receive an email when new articles are posted on . “There are no clear data to suggest that allopurinol is detrimental to renal function in patients with gout,” ...

The allopurinol hypersensitivity syndrome (AHS) consists of severe rash, fever, eosinophilia, and hepatitis and renal failure. [1] It is a feared, albeit rare, complication of therapy and is sometimes ...

Please provide your email address to receive an email when new articles are posted on . Allopurinol is noninferior to febuxostat for gout when dosed appropriately as part of a treat-to-target strategy ...

gout of foot The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum uric acid ...

Improvement observed in estimated glomerular filtration rate in kidney transplant recipients treated with allopurinol for elevated uric acid. Urate-lowering treatment with allopurinol may help ...

Initiating allopurinol during an acute gout attack doesn't adversely affect the resolution of the attack, according to results of a new placebo-controlled, double-blind study. Allopurinol given during ...

The effects of allopurinol treatment on mortality among patients with gout remain uncertain, with a new meta-analysis finding conflicting results. In a systematic review of the literature that ...

Allopurinol (4-hydroxypyrazolo-(3, 4-d) pyrimidine, HPP), a xanthine oxidase inhibitor, offers a new concept in the prevention of the complications of hyperuricemia. By effectively blocking the ...

Poor control of gout leads to recurrent flares of severe pain, work disability, joint damage and activity limitation. The cornerstone of effective management of the disease is long-term serum urate ...