Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, ...

This is a preview. Log in through your library . Abstract Amyloid-β (Aβ) fibrils exhibit self-propagating, molecular-level polymorphisms that may contribute to variations in clinical and pathological ...

Amyloid fibrils appear in many neurodegenerative diseases, and scientists are eager to understand how they form and spread. But amyloids—clumped aggregations of misfolded proteins—can be difficult to ...

The process of alternating elongation and pausing of amyloid β (Aβ) fibrils was captured by combining high-speed atomic force microscopy (HS-AFM) and Monte Carlo simulations. The study revealed the ...

A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies, stacks of peptides like amyloid beta, most notably ...

Amyloid fibril formation of α-synuclein (αS) is associated with multiple neurodegenerative diseases, including Parkinson’s disease (PD). Growing evidence suggests that progression of PD is linked to ...

Amyloid-beta (A-beta) aggregates are tangles of proteins most notably associated with neurodegenerative diseases like Alzheimer’s. Despite its constant stint in the limelight, however, researchers ...

Researchers use microscopy to chart amyloid beta's underlying structure and yield insight into neurodegenerative disease. Amyloid-beta (A-beta) aggregates are tangles of proteins most notably ...

Researchers found that peristaltic pump flow mechanically breaks supersaturation to induce amyloid formation by hen egg white lysozyme, a-synuclein, amyloid b 1-40, and b2-microglobulin. The high ...