The basal ganglia play a critical role in regulating movement, cognitive functions and emotional processing. Disruptions within these subcortical nuclei are increasingly attributed to defects in ...

CARY, N.C. (WTVD) -- At 11 weeks old Stevie Kestner was diagnosed with Biotin-thiamine-responsive basal ganglia disease, a rare condition that only affects a reported 50 people in the world. Before ...

Neurons deep in the brain not only help to initiate movement-they also actively suppress it, and with astonishing precision. This is the conclusion of a new study by researchers at the University of ...

The substantia nigra is a motor nucleus located in the basal ganglia of the midbrain. This brain structure contributes to the body's cognitive and motor functions by sending signals to initiate or ...

Parkinson’s weight loss is increasingly recognised as a key factor in disease progression, linked to frailty, cognitive decline and reduced quality of life.

SNr neurons in the midbrain send precise signals to control movement. Their activity determines which movements actions are initiated or inhibited. Neurons deep in the brain not only help to initiate ...

A few years after the 1918 Spanish Flu pandemic doctors around the world began to notice an increase in new Parkinson’s disease cases. This link between viral infection and increased Parkinson’s risk ...

Researchers have applied a chemogenetic tool in macaque monkeys and suppressed the subthalamic nucleus, a part of the basal ganglia circuitry. The chemogenetic suppression induced unstable movements.