Cell-communication molecules called kinases play a key role in the growth and spread of many cancers. But exactly which kinases are active in a particular cancer is not always clear—there are 1.8 ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

Researchers at Helmholtz Munich, the Heidelberg Faculty of Medicine at Heidelberg University, the German Center for Diabetes ...

We conducted a comprehensive analysis of a manually curated human signaling network containing 1634 nodes and 5089 signaling regulatory relations by integrating cancer‐associated genetically and ...

Brain tumor cells exploit a mechanism normally used by healthy brain cells to promote their own multiplication. Gliomas ...

Researchers at the University of Colorado Anschutz and Indiana University School of Medicine have identified a biological ...

A fluorescent probe for visualizing the signaling dynamics in metastatic cancer cells has been developed. A research team at the University of Turku (Finland), led by Johanna Ivaska and James Conway, ...

Researchers identified a previously unrecognized molecular mechanism cells can use to pass along signals. The finding resolves a longstanding puzzle for how the Hedgehog signaling pathway works—one of ...

By using mRNA molecules to “remodel” parts of the immune system, researchers generated T cells that can slow the growth of ...

In a separate mouse experiment, cells treated with THC formed fewer cancer-cell clusters in the lungs.

Andrew Ko, who led UCSF's trials of daraxonrasib based on discovery science, tells what to know about the medicine, the ...