Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...

Extracellular signal-regulated kinase (ERK) occupies a central node in the mitogen-activated protein kinase (MAPK) cascade, translating a diverse array of extracellular cues into coordinated ...

Cell migration is orchestrated by signal transduction networks that translate extracellular cues into coordinated intracellular responses. Directed migration depends on the establishment of front–back ...

A research team led by Dr. Tetsuya Muramoto from the Faculty of Science at Toho University has demonstrated the mechanisms by which periodic chemical signal frequencies in cells regulate gene ...

cases an external molecule dramatically affects cellular function. Our goal in studying any of these processes is the same: a molecule-by-molecule accounting of information transfer in biological ...

Researchers from the University of Illinois have discovered a key factor responsible for facilitating signal transduction in Cys-loop receptors, providing insight into a longstanding question in the ...

Edited by: James Kling P.A. Hoodless, T. Haerry, S. Abdollah, M. Stapleton, M.B. O'Connor, L. Attisano, J.L. Wrana, "MADR1, a MAD-related protein that functions in ...

Unlike accidental cell death, some cells can actively decide to die through a controlled process. This is called programmed cell death and can occur in different forms, including apoptosis and ...

A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew themselves. Decades of research have shown that disruption of this pathway is a ...