Polyfunctional alkylating agent; activity as an antineoplastic and immunosuppressant Active against a variety of solid tumors, NHL, Hodgkin lymphoma, and ALL Also used in nephrotic syndrome, RA, ...
Patients undergoing matched-donor stem cell transplants lived four times longer without episodes of graft-versus-host disease (GVHD) with post-transplant cyclophosphamide-cyclosporin prophylaxis, a ...
Post–hematopoietic cell transplantation (HCT) prophylaxis using cyclophosphamide to stave off graft-vs-host disease had positive results compared with calcineurin inhibitor–based prophylaxis, ...
In patients undergoing allogeneic hematopoietic stem-cell transplantation (HSCT), a calcineurin inhibitor plus methotrexate has been a standard prophylaxis against graft-versus-host disease (GVHD). A ...
Long-Term (≥5-Year) Remission and Survival After Treatment With Ciltacabtagene Autoleucel in CARTITUDE-1 Patients With Relapsed/Refractory Multiple Myeloma Allogeneic hematopoietic stem cell ...
Cyclophosphamide is also approved to treat minimal change nephrotic syndrome in children a kidney disorder when other treatments have produced intolerable side effects or have failed. This is not a ...
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