Signaling downstream of receptor tyrosine kinase c-Kit has been studied in several different types of cells, including mast cells and immortalized hematopoietic cell lines. 10 Activation of c-Kit by ...
The SLUG transcription factor has been linked with the KIT signalling pathway that is important for gastrointestinal stromal tumour (GIST) tumourigenesis. Its clinical significance in GIST is unknown.
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