Researchers have discovered how unstructured segments of surface proteins regulate the biological function of a cell. Their ...

G protein-coupled receptors (GPCRs) represent the largest family of cell surface receptors, orchestrating a vast array of physiological responses by transducing extracellular signals into ...

GPCRs are a large family of receptors found in the cell membrane of almost all living organisms. They are responsible for cell communication, acting like sentinels between cells, ready to recognise ...

Scientists reveal how G protein-coupled receptors, major therapeutic drug targets, decode critical properties of their ligands. Through an international collaboration, scientists at St. Jude ...

Researchers have uncovered how a protein called MRAP2 acts as a key regulator of hunger. It helps move the appetite receptor MC4R to the cell’s surface, allowing it to send stronger “stop eating” ...

Animals depend on their sense of smell to locate food, identify mates and evade danger. In mammals, olfactory perception typically relies on G protein–coupled receptor (GPCR) pathways. Insects, by ...