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Detailed structure of key hearing protein points way to optimizing gene therapies for deafness
Researchers in Göttingen, Germany, have elucidated the structure and function of otoferlin, a protein that plays a crucial ...
The overexpression of a gene tied to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer's disease (AD), ...
Researchers say findings help to bridge the structure of the genome to its function in managing how genes are turned on and off.
Study of the principles of heredity in microbes, plants and animals. An integrated course in classical and contemporary molecular genetics dealing with topics that include the structure and function ...
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New insights reveal persistent genome structure during cell division
Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can ...
Long interspersed nuclear element-1 (LINE-1 or L1) is the only active, self-copying genetic element in the human ...
Molecular biologists have long believed that the beginning of a gene launched the process of transcription—the process by which a segment of DNA is copied into RNA and then RNA helps make the proteins ...
Whole genome duplication followed by massive gene loss has shaped many genomes, including the human genome. Why some gene duplicates are retained while most perish has puzzled scientists for decades.
For the first time ever, a research team has peered inside a human cell to view Mediator-bound pre-initiation complex, a multi-subunit machine responsible for regulating gene expression. For the first ...
A team of researchers co-led by Michael Frohman, MD, PhD, of Stony Brook University, has identified an important cause of congenital heart disease. They discovered that certain loss of functions in ...
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