The American Journal of Managed Care

Lactate Dehydrogenase Levels Associated With Fatigue, QOL in Patients With PNH

Patients with paroxysmal nocturnal hemoglobinuria (PNH) had decreased quality of life (QOL) and worse fatigue that could be linked to lactate dehydrogenase levels. Researchers found that levels of ...
The American Journal of Managed Care

High LDH Levels Associated With Worse Survival in Newly Diagnosed AML

Elevated white blood cell counts also appear to correlate with shorter overall survival in patients receiving standard induction chemotherapy plus cytarabine for acute myeloid leukemia. High serum ...
Nature

Lactate dehydrogenase-5 (LDH-5) overexpression in non-small-cell lung cancer tissues is linked to tumour hypoxia, angiogenic factor production and poor prognosis

Archival paraffin-embedded biopsy material from 76 primary squamous cell lung carcinomas and 36 lung adenocarcinomas were retrieved, and 3 μm tissue sections were cut on slides (Department of ...
ascopubs.org

Lactate Dehydrogenase 5 Expression in Operable Colorectal Cancer: Strong Association With Survival and Activated Vascular Endothelial Growth Factor Pathway—A Report of the ...

We investigated the immunohistochemical expression of LDH-5 in a series of 128 stage II/III colorectal adenocarcinomas treated with surgery alone. In addition, markers of tumor hypoxia ...
Medscape

Low LDH May Predict Second-Line Bevacizumab CRC Response

BARCELONA — Patients with metastatic colorectal cancer (CRC) who have progressed after first-line chemotherapy plus bevacizumab (Avastin, Genentech) and who have low levels of lactate dehydrogenase ...