Arizona Cardinals TE Trey McBride was flagged for an unsportsmanlike conduct penalty during Week 11’s contest against the San Francisco 49ers. Replay of his catch and tackle showed all he did was signal a first down in the second quarter of action, doing the “nose wipe” celebration, and being flagged.

Kickoff from Raymond James Stadium in Tampa is set for 1 p.m. ET, and the Buccaneers are 3.5-point favorites in the latest Cardinals vs. Buccaneers consensus odds, while the over/under for total points scored is 44.5.

Expert recap and game analysis of the San Francisco 49ers vs. Arizona Cardinals NFL game from November 16, 2025 on ESPN.