Nuclear magnetic resonance (NMR) spectroscopy has emerged as an indispensable tool in elucidating protein dynamics at atomic resolution. In particular, studies on aromatic side chains have revealed ...
Researchers have developed an economical random fractional 13C labeling strategy using methanol for eukaryotic membrane proteins expressed in yeast. This method significantly improves spectral ...
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MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils
One of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain.
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Ageing slows brain protein clearance and shifts synaptic waste to microglia
By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...
MIT chemists used NMR spectroscopy to reveal the disordered “fuzzy coat” surrounding Tau protein fibrils, offering new ...
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