Mechanistically, thirst starts with the excitation of osmoregulatory cells in a brain structure called the lamina terminalis, which is located in the anterior wall of the third ventricle. The lamina ...
Liquid alternative to desmopressin tablets allows for more precise dosing ...
Central diabetes insipidus is a rare condition that can cause extreme thirst and a frequent need to pee. It occurs when there isn’t enough antidiuretic hormone (ADH) in your body. Diabetes insipidus ...
Aquaporin-2 (AQP2) is a critical water channel in the renal collecting ducts that governs water reabsorption and urine concentration. Dysregulation of AQP2, through genetic mutations or acquired ...
PHILADELPHIA--(BUSINESS WIRE)--NephroDI Therapeutics, Inc., a biopharmaceutical company developing NDI-5033 for the X-linked/congenital form of Nephrogenic Diabetes Insipidus (NDI), today announced a ...
X-linked nephrogenic diabetes insipidus (XNDI) is a severe congenital kidney disease caused by mutations in the V2R gene. Currently, there is no effective drug to specifically treat XNDI, mainly ...
What Is Desmoda, and Why Does It Matter? The FDA has approved Desmoda (desmopressin acetate) oral solution for managing central diabetes insipidus (CDI) in adults and children. It is a liquid version ...
Please provide your email address to receive an email when new articles are posted on . A group of representatives from national and international endocrine, nephrology and pediatric societies has ...