Phosphatidylinositol 3-kinase (PI 3K) acts upstream of myriad cellular pathways, including those that regulate protein synthesis and tumorigenesis. In this example, PI 3K phosphorylates the lipid PI ...
The phosphoinositide-3 kinase (PI-3K)/AKT cell survival pathway is an important pathway activated by EGFR signaling. Here we show, that in addition to previously described critical components of this ...
Lithium inhibits inositol monophosphatase of the phosphoinositide (PI) pathway, an effect which was suggested to be responsible for lithium's therapeutic action (Berridge et al, 1982). Lithium reduced ...
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