When the cell's recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and ...

The lysosome is a small membrane bound organelle that can be found in most animal cells. It was once thought that these little sacs were like recycling centers that could take up cellular waste ...

Lysosomes are thought of as cellular organelles that play an important role in recycling proteins and maintaning cells by breaking down stuff that isn’t needed. But new research has found that ...

For the first time, the pathway through which cells repair damaged lysosomes has been observed and described. Lysosomes are the recycling center of a cell, where molecular waste is degraded into the ...

The retromer complex controls protein sorting, transport, and disposal via the endolysosome system. It goes awry in neurodegenerative diseases, but how so remains unclear. Metabolism breaks down in ...

Scientists at Baylor College of Medicine, the Howard Hughes Medical Institute (HHMI) and collaborating institutions report in the journal Nature Cell Biology that lysosomes in roundworms produce ...

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed. In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, ...

When astrocytes transform from homeostatic to reactive, what goes wrong inside them? Martin Kampmann, University of California, San Francisco, and colleagues blame dysfunctional lysosomes. In a ...

If you had to swallow a pouch of toxins, you’d like to be certain the pouch was indestructible. Similarly, every eukaryotic cell seeks to ensure that the membranes of its many miniscule sacs called ...

Ishikawa, Japan - The correct functioning of our cells rests upon the precise orchestration of many complex processes and organelles. Lysosomes—vital cell organelles—are enzyme-filled subunits found ...