On his trip this week to the Middle East, U.S. President Donald Trump will visit Saudi Arabia, Qatar and the United Arab Emirates, though his most pressing regional challenges concern two other countries: Israel and Iran.

Fox News' Greg Palkot reports from Tel Aviv, Israel on the president's upcoming trip to the Middle East.

When President Donald Trump took office in January, he and Israeli Prime Minister Benjamin Netanyahu were closely aligned on how to approach the most pressing issues in their relationship: the war in Gaza and aggression from Iran.

Nadergholi Ebrahimi has asked Supreme Leader Khamenei to rethink Iran's nuclear policy if negotiations with the U.S. collapse.

The latest round of high stakes nuclear talks between Iran and the US have ended, with Tehran calling them difficult but with both sides agreeing to further negotiations.

The talks seek to limit Iran’s nuclear program in exchange for the lifting of some of the economic sanctions the U.S. has imposed.