In animals the process of programmed cell death, or apoptosis, is thought to be mediated by caspases, a family of cysteine proteases that cleave one another and key intracellular proteins, killing the ...
The use of gene array analysis to determine down-stream molecular expression patterns of trastuzumab (T) treatment No significant financial relationships to disclose. This is an ASCO Meeting Abstract ...
Expression profiles associated with disease progression in non-small cell lung cancer. Background: Cisplatin is a platinum-based chemotherapeutic drug used for treating a variety of human cancers such ...
Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...
Caspase-2-mediated cleavage of tau at Asp314 generates a neurotoxic fragment, Δtau314, that drives early synaptic dysfunction in Alzheimer’s disease (AD) and frontotemporal dementia (FTD). This ...
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