By 2030, the population in the United States aged 65 and older is expected to reach 71 million or about 20% of Americans.

Aging is associated with progressive alterations in endocrine signalling that disrupt the regulation of energy balance and metabolic homeostasis. Changes in ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Two new papers describe a significant advance in understanding the complex functions of the metabolic network. Two papers published today in the journal Nature describe a significant advance in ...

This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells ...

Clinical outcomes of a prospective multicenter study evaluating a combined circulating tumor DNA (ctDNA) and RNA (ctRNA) liquid biopsy assay in metastatic non-small cell lung cancer (NSCLC). This is ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...

New research shows fructose isn’t just another calorie—it acts like a hormone, triggering fat storage, blood pressure changes, and energy depletion. This unique metabolic pathway bypasses the body’s ...

In the field of plant biology, a growing body of evidence shows that plants possess the remarkable ability to “remember” previous encounters with ...