Cardinals 41-22 in Week 11. Key stats, record milestones, and standout performances from Purdy, McCaffrey, Kittle, and the ...

Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

The Arizona Cardinals suffered another blowout loss. On Sunday at State Farm Stadium, they gave up a 98-yard kickoff return ...

SANTA CLARA, Calif. (AP) — Brock Purdy returned to the lineup and the San Francisco 49ers scored their most points in nearly ...

The Arizona Cardinals are back in action in Week 11, facing the San Francisco 49ers for the second time this season. The 6-4 ...

A healthy 49ers offense turned to its stars in San Francisco's 41-22 victory over the Arizona Cardinals on Sunday at State ...

A former NFL star accused the Arizona Cardinals of point-shaving against the 49ers on Sunday after San Francisco cruised to a ...

Brock Purdy threw three touchdown passes in his return from a toe injury, Christian McCaffrey had two rushing touchdowns and ...

The San Francisco 49ers picked off Arizona's Jacoby Brissett twice, a defensive counter to the QB's NFL record 47 completions ...

Brock Purdy passed for 200 yards and three touchdowns in his first game since Sept. 28, Christian McCaffrey scored three ...

The 49ers cruised into their bye week in style on Sunday with a 26-8 victory over the Cleveland Browns, a win they were clearly happy to get. The game was ...

Cardinals running back Emari Demercado exited the second quarter of his team's game against the San Francisco 49ers with an ...