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  1. p450 and porphyrias? | USMLE Forums

    Mar 1, 2011 · Remember that p450 is cytochrome p450 - it uses a heme molecule in the active site for electron transfer. More demand for cytochrome = more demand for heme; in someone …

  2. NBME 13 Discussion | USMLE Forums

    Jul 20, 2012 · we all know that gemfibrozil and simvastatin combo will lead to severe myopathy. is it due to gemfibrozil inhibiting cytochrome p450 leading to increased levels of statin and …

  3. Remembering pharmacology | USMLE Forums

    Jun 8, 2012 · I am facing some trouble in regards to memorizing cytochrome p 450 interactions of drugs. All most any drug i read through either enhances or inhibits cyp 450 and there are …

  4. Step 1 Experience | USMLE Forums

    Oct 4, 2015 · I am going to cover all the weird concepts tested as well (pelvic anatomy, incontinence, P450, upper and lower anatomy, & NBME questions that helped from old forms, …

  5. NBME 16 Diskussion | USMLE Forums

    Mar 12, 2014 · Hallo zusammen. Ich habe kürzlich nbme 16 gemacht. Wenn jemand bei den Antworten helfen und an der Diskussion teilnehmen kann, bitte, Sie sind herzlich willkommen. …

  6. Test your knowledge #21! (Pharmacology) | USMLE Forums

    Feb 24, 2011 · Amiodarone is metabolised to desmethylamiodarone mostly by CYP3A4 in the liver. CYP3A4 is induced by habitual phenytoin use, so amiodarone may be more quickly …

  7. Jun 24, 2006 · Acetaminophen toxicity - 2 Acute alcoholic intake can reduce the risk of hepatic injury by Acetaminophen because it competes with CYP2E1, so there is less production of …

  8. low score in nbme 13 | USMLE Forums

    Dec 28, 2015 · Jump to Latest 1.8K views 4 replies 3 participants last post by darbi Dec 30, 2015 P P450 Discussion starter 16 posts · Joined 2015 #1 ·Dec 28, 2015 hi guys, i got low score in …

  9. Anti-seizure medications lower efficacy of OCP by induction of P450. All antiseizure meds lower efficacy except gabapentin and valproate. OCP: if taken perfectly (never miss a pill, takes pill …

  10. A 32-year-old man with hypocalcemia | USMLE Forums

    Dec 7, 2012 · Carbamazepine and other medications including phenytoin, rifampin, and theophylline increase the activity of cytochrome P450 enzymes in the liver that inactivate …